Research article2025Peer reviewedOpen access
A novel cross-validated machine learning based Alertix-Cancer Risk Index for early detection of canine malignancies
Sharif, Hanan; Belaghi, Reza Arabi; Jagarlamudi, Kiran Kumar et al.
Publications
2025
2024
Research article2024Peer reviewed
Clinical significance of the TK1 specific activity in the early detection of ovarian cancer
Osredkar, Josko; Jagarlamudi, Kiran Kumar; Cviic, Diana et al.
2023
Research article2023Peer reviewedOpen access
A Dual Biomarker TK1 Protein and CA125 or HE4-Based Algorithm as a Better Diagnostic Tool than ROMA Index in Early Detection of Ovarian Cancer
Cviic, Diana; Jagarlamudi, Kiran; Meglic, Leon et al.
Research article2023Peer reviewedOpen access
A monoclonal antibody-based sandwich ELISA for measuring canine Thymidine kinase 1 protein and its role as biomarker in canine lymphoma
Sharif, Hanan; Saellstrom, Sara; Kolli, Bhavya et al.
2022
Research article2022Peer reviewedOpen access
Mutational analyses of human thymidine kinase 2 reveal key residues in ATP-Mg2+ binding and catalysis
Wang, Liya; Eriksson, Staffan.
Research article2022Peer reviewedOpen access
Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase
Frisk, Junmei Hu; Pejler, Gunnar; Eriksson, Staffan et al.
Research article2022Peer reviewedOpen access
Structural and functional analysis of human thymidylate kinase isoforms
Frisk, Jun Mei Hu; Pejler, Gunnar; Eriksson, Staffan et al.
Research article2022Peer reviewedOpen access
Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders
Frisk, Junmei Hu; Orn, Stefan; Pejler, Gunnar et al.
Research article2022Peer reviewedOpen access
Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies
Saellstrom, S.; Sharif, H.; Jagarlamudi, K. K. et al.
Research article2022Peer reviewedOpen access
Analytical and clinical characterization of an optimized dual monoclonal sandwich ELISA for the quantification of thymidine kinase 1 (TK1) protein in human blood samples
Jagarlamudi, K. K.; Swinkels, L.; Zupan, M. et al.
2021
Research article2021Peer reviewedOpen access
Biochemical Characterizations of Human TMPK Mutations Identified in Patients with Severe Microcephaly: Single Amino Acid Substitutions Impair Dimerization and Abolish Their Catalytic Activity
Frisk, Jun Mei Hu; Vanoevelen, J. M.; Bierau, Jörgen et al.
Research article2021Peer reviewedOpen access
Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker
Wang, Liya; Sharif, Hanan; Saellstrom, Sara et al.
Research article2021Peer reviewedOpen access
Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma
Wang, Liya; Unger, Lucia; Sharif, Hanan et al.
Research article2021Peer reviewedOpen access
Serum concentrations of Thymidine kinase 1 measured using a novel antibody-based assay in patients with Hodgkin Lymphoma
Ulfstedt, Johan Mattsson; Venge, Per; Holmgren, Sofia et al.
Research article2021Peer reviewedOpen access
Blood biomarker algorithms for the diagnosis of mycoplasma pneumoniae respiratory infections
Venge, Per; Eriksson, Staffan; Pauksen, Karlis.
2020
Research article2020Peer reviewed
Identification of a novel thymidylate kinase activity
Frisk, Junmei Hu; Eriksson, Staffan; Pejler, Gunnar et al.
Research article2020Peer reviewed
The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs
Sun, Ren; Eriksson, Staffan; Wang, Liya.
Research article2020Peer reviewedOpen access
AroCell TK 210 ELISA for determination of TK1 protein: age-related reference ranges and comparison with other TK1 assays
Kumar, Jagarlamudi Kiran; Holmgren, Sofia; Levedahl, Kerstin Hamberg et al.
Research article2020Peer reviewedOpen access
Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency
Wang, Liya; Sun, Ren; Eriksson, Staffan.
2019
Research article2019Peer reviewed
The combination of AroCell TK 210 ELISA with Prostate Health Index or prostate-specific antigen density can improve the ability to differentiate prostate cancer from noncancerous conditions
Jagarlamudi, Kiran Kumar; Zupan, Mojca; Kumer, Kristina et al.
2018
Research article2018Peer reviewed
Doxorubicin effects on leukemia and breast cancer cells in culture on the TK1 protein levels using AroCell TK 210 ELISA: a tool for drug development
Jagarlamudi, K. K.; Wang, L.; Eriksson, S..
Research article2018Peer reviewedOpen access
Negative Cooperative Binding of Thymidine, Ordered Substrate Binding, and Product Release of Human Mitochondrial Thymidine Kinase 2 Explain Its Complex Kinetic Properties and Physiological Functions
Wang, Liya; Zhang, Li; Sun, Ren et al.
2017
Research article2017Peer reviewedOpen access
Thymidine kinase 1 expression in ovarian serous adenocarcinoma is superior to Ki-67: A new prognostic biomarker
Wang, Jianjun; Liu, Qi; Zhou, Xiaodie et al.
2016
Research article2016Peer reviewedOpen access
A clinical evaluation of the TK 210 ELISA in sera from breast cancer patients demonstrates high sensitivity and specificity in all stages of disease
Kumar, J. Kiran; Aronsson, A. C.; Pilko, G. et al.
2015
Review article2015Peer reviewedOpen access
The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling
Engström, Wilhelm; Eriksson, Staffan; Bisson, William H.