Diverse plant viruses: a toolbox for dissection of cellular pathways

Abstract

Research in virology has usually focused on one selected host-virus pathosystem to examine the mechanisms underlying a particular disease. However, as exemplified by the mechanistically versatile suppression of antiviral RNA silencing by plant viruses, there may be functionally convergent evolution. Assuming this is a widespread feature, we propose that effector proteins from diverse plant viruses can be a powerful resource for discovering new regulatory mechanisms of distinct cellular pathways. The efficiency of this approach will depend on how deeply and widely the studied pathway is integrated into viral infections. Beyond this, comparative studies using broad virus diversity should increase our global understanding of plant-virus interactions.

Published in

Journal of Experimental Botany
2019, volume: 70, number: 12, pages: 3029-3034
Publisher: OXFORD UNIV PRESS

SLU Authors

• Shukla, Aayushi

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

• Lòpez Gonzàlez, Silvia

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

• Hoffmann, Gesa

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

• Hafrén, Anders

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

Associated SLU-program

SLU Plant Protection Network
AMR: Virus

UKÄ Subject classification

Botany

Publication identifier

• DOI: https://doi.org/10.1093/jxb/erz122

Permanent link to this page (URI)

https://res.slu.se/id/publ/102005