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Sammanfattning

Continued climate change impose multiple stressors on crops, including pathogens, salt, and drought, severely impacting agricultural productivity. Innovative solutions are necessary to develop resilient crops. Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility. We show that knockout or silencing of Parakletos enhances resistance to oomycete, fungi, bacteria, salt, and drought, whereas its overexpression reduces resistance. In response to biotic stimuli, Parakletos-overexpressing plants exhibit reduced amplitude of reactive oxygen species and Ca2+ signalling, and silencing Parakletos does the opposite. Parakletos homologues have been identified in all major crops. Consecutive years of field trials demonstrate that Parakletos deletion enhances resistance to Phytophthora infestans and increases yield. These findings demark a susceptibility gene, which can be exploited to enhance crop resilience towards abiotic and biotic stresses in a low-input agriculture.

Publicerad i

Nature Communications
2024, volym: 15, nummer: 1, artikelnummer: 5224

SLU författare

Associerade SLU-program

SLU Nätverk växtskydd

Globala målen (SDG)

SDG2 Ingen hunger
SDG13 Bekämpa klimatförändringarna

UKÄ forskningsämne

Jordbruksvetenskap
Växtbioteknologi

Publikationens identifierare

  • DOI: https://doi.org/10.1038/s41467-024-49584-4

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/131173