SMARTER-database: a tool to integrate SNP array datasets for sheep and goat breeds

Sammanfattning

Underutilized sheep and goat breeds can adapt to challenging environments due to their genetics. Integrating publicly available genomic datasets with new data will facilitate genetic diversity analyses; however, this process is complicated by data discrepancies, such as outdated assembly versions or different data formats. Here, we present the SMARTER-database, a collection of tools and scripts to standardize genomic data and metadata, mainly from SNP chip arrays on global small ruminant populations, with a focus on reproducibility. SMARTER-database harmonizes genotypes for about 12,000 sheep and 6,000 goats to a uniform coding and assembly version. Users can access the genotype data via File Transfer Protocol and interact with the metadata through a web interface or using their custom scripts, enabling efficient filtering and selection of samples. These tools will empower researchers to focus on the crucial aspects of adaptation and contribute to livestock sustainability, leveraging the rich dataset provided by the SMARTER-database.

Nyckelord

Animal and Plant Sciences; Bioinformatics; Animal Genetics

Publicerad i

Gigabyte
2024, volym: 2024, artikelnummer: 139

SLU författare

• Johansson, Anna Maria

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Bioinformatik (beräkningsbiologi)
Genetik och förädling inom lantbruksvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.46471/gigabyte.139

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/139841