Analyzing Quinoa Seeds: LC-MS/MS and GC-MS/MS Approaches for Identifying a Nutrient-Rich Functional Food in Alzheimer's and Diabetes Care

Sammanfattning

Quinoa is a versatile, nutrient-dense, gluten-free pseudocereal, increasingly recognized for its potential health benefits, particularly in managing diabetes mellitus and Alzheimer's disease-two conditions with growing links. Recent research on 14 quinoa genotypes explored fatty oil composition and bioactive potential of quinoa extracts. Linoleic acid was predominant fatty acid (46.60%-56.33%), whereas alanine was the most concentrated amino acid across all active extracts (192.4887-1578.0355 nmol/mL). French Vanilla hexane extract exhibited the strongest alpha-glucosidase inhibition (75.71%), with Santa Ana hexane extract showing the highest alpha-amylase inhibition (28.58%). Additionally, Titicaca hexane extract displayed notable acetylcholinesterase inhibition (22.22%), and Moqu Arochilla methanol extract had the most potent butyrylcholinesterase inhibition (47.20%). Antioxidant assays revealed that Salcedo and French Vanilla extracts had exceptional 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, with positive correlations found between total phenolic content and antioxidant activity (DPPH, beta-carotene, FRAP). These findings emphasize quinoa's potential as a functional food, offering significant benefits for disease management.

Nyckelord

Alzheimer's disease; amino acid; diabetes mellitus; fatty oil; quinoa

Publicerad i

Chemistry & Biodiversity
2024
Utgivare: WILEY-V C H VERLAG GMBH

SLU författare

• Coban, Furkan

  • Institutionen för växtförädling, Sveriges lantbruksuniversitet
    
  • Ataturk University

UKÄ forskningsämne

Biokemi och molekylärbiologi
Livsmedelsvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.1002/cbdv.202401727

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/139877