Celma, Alberto
- Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences
Abstract
Ion mobility separation (IMS) was hyphenated to high resolution mass spectrometry (HRMS) instruments as an additional separative dimension to chromatography and mass spectrometry. In IMS, ion characteristics such as shape and size are studied by observing their response upon an acceleration in a buffer gas by means of an electric field. The extra physical separation orthogonal to chromatography (often liquid chromatography) and mass spectrometry provides relevant and meaningful information for the enhanced identification of organic micropollutants. Additionally, the utilization of IMS-HRMS instruments for the analysis of organic micropollutants in complex matrices provides, among others, the removal of coeluting interferent substances, the enhancement of signal-to-noise ratio for compounds of interest, or even the reduction of false positive detections. All these as well as other benefits of IMS are discussed in depth along the sections of this chapter. Special attention is also drawn to topics in which further research or hardware improvements are needed. Overall, the role of IMS-HRMS for the analysis of organic micropollutants in environmental samples is examined.
Keywords
Collision cross section; Identification confidence; Ion mobility separation; Pollutants; Screening
Published in
The handbook of environmental chemistry
2025, number: 138, pages: 1-22
Title: Screening of Pollutants in the Environment : Non-target Strategies and Latest Trends
Publisher: Springer Science and Business Media Deutschland GmbH
SLU Authors
UKÄ Subject classification
Environmental Sciences
Analytical Chemistry
Publication identifier
- DOI: https://doi.org/10.1007/698_2023_1055
- ISBN: 978-3-031-90685-5
- eISBN: 978-3-031-90686-2
Permanent link to this page (URI)
https://res.slu.se/id/publ/145071