Using step selection functions to analyse human mobility using telemetry data in infectious disease epidemiology: a case study of leptospirosis

Ruiz Cuenca, Pablo; Souza, Fabio N.; Coutinho Do Nascimento, Roberta; Goncalves Da Silva, Ariane; Eyre, Max T.; Santana, Juliet O.; de Oliveira, Daiana; Ribeiro De Souza, Emile, V; Palma, Fabiana G.; De Carvalho Santiago, Diogo C.; Dos Santos Ribeiro, Priscyla; Ferreira Dos Santos, Priscilla Elizabeth; Khalil, Hussein; Read, Jonathan M.; Cremonese, Cleber; Costa, Federico; Giorgi, Emanuele

doi:10.7554/eLife.107153

Forskningsartikel2025Vetenskapligt granskadÖppen tillgång

Using step selection functions to analyse human mobility using telemetry data in infectious disease epidemiology: a case study of leptospirosis

Ruiz Cuenca, Pablo; Souza, Fabio N.; Coutinho Do Nascimento, Roberta; Goncalves Da Silva, Ariane; Eyre, Max T.; Santana, Juliet O.; de Oliveira, Daiana; Ribeiro De Souza, Emile, V; Palma, Fabiana G.; De Carvalho Santiago, Diogo C.; Dos Santos Ribeiro, Priscyla; Ferreira Dos Santos, Priscilla Elizabeth; Khalil, Hussein; Read, Jonathan M.; Cremonese, Cleber; Costa, Federico; Giorgi, Emanuele

Sammanfattning

Background:Human movement plays a critical role in the transmission of infectious diseases, especially those with environmental drivers like leptospirosis-a zoonotic bacterial infection linked to mud and water contact. Using GPS loggers, we collected detailed telemetry data to understand how fine-scale movements can be analysed in the context of an infectious disease. Methods:We recruited individuals living in urban slums in Salvador, Brazil, to analyse how they interact with environmental risk factors such as domestic rubbish piles, open sewers, and a local stream. We aimed to identify differences in movement patterns inside the study areas by gender, age, and leptospirosis serological status. Step selection functions, a spatio-temporal model used in animal movement ecology, estimated selection coefficients to represent the likelihood of movement toward specific environmental factors. Results:With 128 participants wearing GPS devices for 24-48 hr, recording locations every 35 s during active daytime hours, we segmented movements into morning, midday, afternoon, and evening. Our results suggested women moved closer to the central stream and farther from open sewers compared to men, while serologically positive individuals avoided open sewers. Conclusions:This study introduces a novel method for analysing human telemetry data in infectious disease research.Funding:Funding provided by Wellcome Trust, UK Medical Research Council, Brazilian National Research Council, Reckitt Global Hygiene Institute, and National Institute of Allergy and Infectious Diseases.

Nyckelord

leptospirosis; human movement; GPS; urban health; infectious diseases; zoonosis

Publicerad i

eLife
2025, volym: 14, artikelnummer: RP107153
Utgivare: eLIFE SCIENCES PUBL LTD

SLU författare

Khalil, Hussein
- Institutionen för vilt, fisk och miljö, Sveriges lantbruksuniversitet

UKÄ forskningsämne

Epidemiologi

Publikationens identifierare

DOI: https://doi.org/10.7554/eLife.107153

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/145245