GABAergic anxiolytic drug in water increases migration behaviour in salmon

Sammanfattning

Migration is an important life-history event in a wide range of taxa, yet many migrations are influenced by anthropogenic change. Although migration dynamics are extensively studied, the potential effects of environmental contaminants on migratory physiology are poorly understood. In this study we show that an anxiolytic drug in water can promote downward migratory behaviour of Atlantic salmon (Salmo salar) in both laboratory setting and in a natural river tributary. Exposing salmon smolt to a dilute concentration of a GABAA receptor agonist (oxazepam) increased migration intensity compared with untreated smolt. These results implicate that salmon migration may be affected by human-induced changes in water chemical properties, such as acidification and pharmaceutical residues in wastewater effluent, via alterations in the GABAA receptor function.

Publicerad i

Nature Communications
2016, volym: 7, artikelnummer: 13460

SLU författare

• Hellström, Gustav

  • Umeå Universitet

• Klaminder, Jonatan

  • Umeå Universitet

• Persson, Lo

  • Institutionen för vilt, fisk och miljö, Sveriges lantbruksuniversitet
    

• Alanärä, Anders

  • Institutionen för vilt, fisk och miljö, Sveriges lantbruksuniversitet
    

• Jonsson, Micael

  • Umeå Universitet

• Brodin, Tomas

  • Umeå Universitet

Globala målen (SDG)

SDG6 Rent vatten och sanitet för alla
SDG14 Hav och marina resurser

UKÄ forskningsämne

Farmakologi och toxikologi
Fisk- och akvakulturforskning
Ekologi

Publikationens identifierare

• DOI: https://doi.org/10.1038/ncomms13460

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/78270