Cellular and humoral immune alterations during the clinical and recovery phases of experimental swine dysentery

Sammanfattning

Pigs were inoculated with B.hyodysenteriae. Blood was sampled before inoculation, at clinical signs of swine dysentery and during 3 weeks of recovery. Dysentery pigs had elevated levels of Serum Amyloid A and circulating neutrophils, monocytes, CD8+ cells and activated (CD45RA) lymphocytes during dysentery. The CD8+ cells where mainly CD4and CD8. There was a decrease in B cells and an increase in  T cells after inoculation. Serum antibodies where present at day 7 of the recovery from clinical symptoms and onwards. The alterations in protein metabolism and its role will also be addressed

SLU författare

• Kruse, Robert

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Andersson, Märit

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Råsbäck, Therese

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Johannisson, Anders

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Fellström, Claes

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Jensen Waern, Marianne

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Veterinärmedicin
Husdjursvetenskap

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/9600